CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 840
Study Number Lead Group Study Title CIRB Study Status
A151804 Alliance Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events Adult CIRB - Late Phase Emphasis Available to Open
NRG-BN007 NRG A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab versus Temozolomide in Patients with Newly Diagnosed MGMT (Tumor O-6-Methylganine DNA Methyltransferase) Unmethylated Glioblastoma Adult CIRB - Late Phase Emphasis Available to Open
EA5161 ECOG-ACRIN Randomized Phase II Clinical Trial of Cisplatin/Carboplatin and Etoposide (CE) alone or in Combination with Nivolumab as Frontline Therapy for Extensive Stage Small Cell Lung Cancer (ED-SCLC) Adult CIRB - Late Phase Emphasis Available to Open
S1802 SWOG Phase III Randomized Trial of Standard Systemic Therapy (SST) versus Standard Systemic Therapy Plus Definitive Treatment (Surgery or Radiation) of the Primary Tumor in Metastatic Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z6051 ACSOG A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer Adult CIRB - Late Phase Emphasis Available to Open
S0227 SWOG Phase III Randomized Trial of Cisplatin/Paclitaxel Versus Cisplatin/Gemcitabine in Recurrent; Persistent; or Metastatic Carcinoma of the Cervix Adult CIRB - Late Phase Emphasis Completed
GOG-0258 GOG A Randomized Phase III Trial of Cisplatin and Tumor Volume Directed Irradiation Followed by Carboplatin and Paclitaxel vs. Carboplatin and Paclitaxel for Optimally Debulked; Advanced Endometrial Carcinoma Adult CIRB - Late Phase Emphasis Available to Open
NRG-GU002 NRG Phase II-III Trial of Adjuvant Radiotherapy and Androgen Deprivation following Radical Prostatectomy with or without Adjuvant Docetaxel Adult CIRB - Late Phase Emphasis Available to Open
CALGB-49808 CALGB A 2 X 2 X 2 Factorial Randomized Phase III Trial of Multimodality Therapy Comparing 4 Cycles of Doxorubicin and Cyclophosphamide with or without Dexrazoxane (AC +/- Z) Followed by 12 Weeks of Weekly Paclitaxel with or without Trastuzumab (T H) Followed by Local Therapy Followed by 40 Weeks of Weekly Trastuzumab or none in Women with HER-2+ STAGE IIIA; IIIB or Regional Stage IV Breast Cancer **ADMINISTRATIVELY COMPLETED as of December 15; 2002** Adult CIRB - Late Phase Emphasis Completed
A091605 Alliance A Randomized Phase II Study of anti-PD1 antibody [MK-3475 (pembrolizumab)] alone versus anti- PD1 antibody plus Stereotactic Body Radiation therapy in advanced Merkel Cell Carcinoma Adult CIRB - Late Phase Emphasis Available to Open
Displaying 1 - 10 of 840