Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|CITN-14||CITN||A Randomized Phase II Study of Atezolizumab (MPDL3280A) plus Recombinant Human IL-7 (CYT107) in patients with locally advanced or metastatic urothelial carcinoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|MAY2017-09-01||CLO-Mayo Clinic||Phase I Double-Blind, Placebo-Controlled Trial of 27 mg Dolcanatide (SP-333) to Demonstrate Colorectal Bioactivity in Healthy Volunteers||Cancer Prevention and Control CIRB||Available to Open|
|A071102||Alliance||A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation||Adult CIRB - Late Phase Emphasis||Available to Open|
|10220||ETCTN||A Phase II Basket Trial of Glutaminase Inhibitor (BeGIN) CB-839 HCl in Patients with NF1 Aberrations, NF1 Mutant Malignant Peripheral Nerve Sheath Tumors (MPNST), KEAP1/NRF2 and LKB1 Aberrant Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|NRG-GI007||NRG||Phase I Trial with Expansion Cohort of OBP-301 (Telomelysin™) and Definitive Chemoradiation for Patients with Locally Advanced Esophageal and Gastroesophageal Adenocarcinoma Who Are Not Candidates for Surgery||Adult CIRB - Late Phase Emphasis||Available to Open|
|9878||ETCTN||A Phase 1/2 Trial of Erlotinib and Onalespib lactate in EGFR-Mutant Non-Small Cell Lung Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|MAY2015-05-01||CLO-Mayo Clinic||Randomized, double-blind, placebo-controlled trial of Meriva® (curcuminoids) as a candidate chemoprevention agent for gastric carcinogenesis||Cancer Prevention and Control CIRB||Available to Open|
|8329||ETCTN||A Phase I/II Trial of ABT-888, an Inhibitor of Poly(ADP-ribose) Polymerase (PARP), and Topotecan (TPT) in Patients with Solid Tumors (Phase I) and Relapsed Ovarian Cancer or Primary Peritoneal Cancer (Phase II) After Prior Platinum Containing First-Line Chemotherapy||Adult CIRB - Early Phase Emphasis||Available to Open|
|CCTG CE.7||NCCTG||A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA6134||ECOG-ACRIN||DREAMseq (Doublet, Randomized Evaluation in Advanced Melanoma Sequencing) A Phase III Trial||Adult CIRB - Late Phase Emphasis||Available to Open|