Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|ABTC-1802||ABTC||A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor||Adult CIRB - Late Phase Emphasis||Available to Open|
|ADVL1522||COG||A Phase 2 Study of IMGN901 (Lorvotuzumab Mertansine; IND# 126953; NSC# 783609) in Children with Relapsed or Refractory Wilms Tumor; Rhabdomyosarcoma; Neuroblastoma; Pleuropulmonary Blastoma; Malignant Peripheral Nerve Sheath Tumor (MPNST) and Synovial Sarcoma||Pediatric CIRB||Available to Open|
|EAQ172||ECOG-ACRIN||Optimizing Immunosuppression for Steroid- Refractory Anti-PD-1/PD-L1 Pneumonitis||Cancer Prevention and Control CIRB||Available to Open|
|ACNS0831||COG||Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|N1048||NCCTG||A Phase II/III Trial of Neoadjuvant FOLFOX; with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0415||RTOG||A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT versus Conventionally Fractionated 3D-CRT/IMRT in Patients with Favorable-Risk Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1702||SWOG||A Phase II Study of Isatuximab (SAR650984) for Patients with Previously Treated AL Amyloidosis||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1706||SWOG||A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-100104||CALGB||A Phase III Randomized; Double-Blind Study of Maintenance Therapy with CC-5013 (NSC #703813; IND#70116) or Placebo Following Autologous Stem Cell Transplantation for Multiple Myeloma||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-LU005||NRG||Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab||Adult CIRB - Late Phase Emphasis||Available to Open|