Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|10056||ETCTN||A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|CALGB-10501||CALGB||A Phase III Intergroup CLL Study of Asymptomatic Patients with Untreated Chronic Lymphocytic Leukemia Randomized to Early Intervention Versus Observation with Later Treatment in the High Risk Genetic Subset with IgVh Unmutated Disease <br>||Adult CIRB - Late Phase Emphasis||Available to Open|
|UWI2016-08-01||CLO-University of Wisconsin||Pilot Study of Daily Exemestane in Women with Complex Atypical Hyperplasia of the Endometrium / Endometrial Intraepithelial Neoplasia or Grade 1 Endometrial Cancer||Cancer Prevention and Control CIRB||Available to Open|
|9767||ETCTN||An Open Label; Multicenter; Single arm Phase II study to evaluate the Activity and Tolerability of the novel mTOR Inhibitor; MLN0128 (TAK-228); in patients with Locally Advanced or Metastatic Transitional Cell Carcinoma of the urothelial tract whose tumors harbor a TSC1 and/or a TSC2 mutation||Adult CIRB - Early Phase Emphasis||Available to Open|
|ALTE15N2||COG||LEAHRN (Late Effects After High-Risk Neuroblastoma) Study||Pediatric CIRB||Available to Open|
|10219||ETCTN||Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma||Adult CIRB - Early Phase Emphasis||Available to Open|
|EA2186||ECOG-ACRIN||A Randomized Phase II Study of Gemcitabine and Nab-Paclitaxel Compared with 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan in Older Patients with Treatment Naïve Metastatic Pancreatic Cancer (GIANT)||Adult CIRB - Late Phase Emphasis||Available to Open|
|A031801||Alliance||A Phase II Randomized Trial of Radium-223 Dichloride and Cabozantinib in Patients with Advanced Renal Cell Carcinoma with Bone Metastasis (RADICAL)||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-CC006||NRG||A Survey Study to Evaluate Physician Attitudes and Perceptions Regarding a Non-Surgical Approach to Breast Cancer Treatment||Cancer Prevention and Control CIRB||Available to Open|
|ALTE11C2||COG||Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy: A Limited Institution Non-Therapeutic Study||Pediatric CIRB||Available to Open|