Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|E1305||ECOG||A Phase III Randomized Trial of Chemotherapy with or without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|NCIC-BR.19||NCIC CTG||A Phase III Prospective Randomized; Double-Blind; Placebo-Controlled Trial of the Epidermal Growth Factor Receptor Antagonist; ZD1839 (IRESSA) in Completely Resected Primary Stage IB; II and IIIA Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|A031702||Alliance||Phase II Study of Cabozantinib in Combination with Nivolumab and Ipilimumab in Rare Genitourinary Tumors||Adult CIRB - Late Phase Emphasis||Available to Open|
|A041501||Alliance||A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (A Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) with Newly Diagnosed Precursor B-Cell ALL||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0521||SWOG||A Randomized Trial of Maintenance versus Observation for Patients with Previously Untreated Low and Intermediate Risk Acute Promyelocytic Leukemia (APL); Phase III||Adult CIRB - Late Phase Emphasis||Completed|
|EA2187||ECOG-ACRIN||A Phase 2 Study of Pevonedistat in Combination with Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA8171||ECOG-ACRIN||Multiparametric MRI (mpMRI) for Preoperative Staging and Treatment Planning for Newly-Diagnosed Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|E3201||ECOG||Intergroup Randomized Phase III Study of Postoperative Irinotecan; 5-Fluorouracil and Leucovorin Vs Oxaliplatin; 5-Fluorouracil and Leucovorin Vs 5-Fluorouracil and Leucovorin For Patients with Stage II or III Rectal Cancer Receiving Either Preoperative Radiation and 5-Fluorouracil or Postoperative Radiation and 5-Fluorouracil||Adult CIRB - Late Phase Emphasis||Completed|
|NRG-BN007||NRG||A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab versus Temozolomide in Patients with Newly Diagnosed MGMT (Tumor O-6-Methylganine DNA Methyltransferase) Unmethylated Glioblastoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|A031801||Alliance||A Phase II Randomized Trial of Radium-223 Dichloride and Cabozantinib in Patients with Advanced Renal Cell Carcinoma with Bone Metastasis (RADICAL)||Adult CIRB - Late Phase Emphasis||Available to Open|