CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ARET12P1 | COG | A Multi-institutional Feasibility Study of Intra-Arterial Chemotherapy Given in the Ophthalmic Artery of Children with Retinoblastoma | Pediatric CIRB | Available to Open |
| 9673 | ETCTN | A Multi-Institutional Phase II Study of Nivolumab in Refractory Metastatic Squamous Cell Carcinoma of the Anal Canal | Adult CIRB - Early Phase Emphasis | Available to Open |
| AHOD0831 | COG | A Non-Randomized Phase III Study of Response Adapted Therapy for the Treatment of Children with Newly Diagnosed High Risk Hodgkin Lymphoma: A Groupwide Phase III Study | Pediatric CIRB | Available to Open |
| NRG-CC008 | NRG | A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk] | Cancer Prevention and Control CIRB | Available to Open |
| 10015 | ETCTN | A Non-Randomized; Open-Label; Phase 2 Study of Trametinib in Patients with Unresectable or Metastatic Epithelioid Hemangioendothelioma | Adult CIRB - Early Phase Emphasis | Available to Open |
| PBTC-049 | PBTC | A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma | Pediatric CIRB | Available to Open |
| PBTC-053 | PBTC | A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma | Pediatric CIRB | Available to Open |
| ADVL06B1 | COG | A Pharmacokinetic-Pharmacodynamic-Pharmacogenetic Study of Actinomycin-D and Vincristine in Children with Cancer: A Group-Wide Non-Therapeutic Study | Pediatric CIRB | Completed |
| 10066 | ETCTN | A Phase 1 / 2 Study of Olaparib in Combination with Ramucirumab in Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10076 | ETCTN | A Phase 1 Dose-Escalation And Exploratory Dose Expansion Study Of AMG 232 In Combination With Carfilzomib, Lenalidomide, And Dexmethasone In Relapsed And/Or Refractory Myeloma | Adult CIRB - Early Phase Emphasis | Available to Open |