CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 820
Study Number Lead Group Study Title CIRB Study Status
NRG-BR002 NRG A Phase IIR/III Trial of Standard of Care Therapy with or without Stereotactic Body Radiotherapy (SBRT) and/or Surgical Ablation for Newly Oligometastatic Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
CALGB-70301 CALGB Quality of Life; Employment; and Informal Care Cost Analysis in Women Receiving Adjuvant Chemotherapy for Breast Cancer with 0-3 Positive Axillary Lymph Nodes: Companion to CALGB 40101 Adult CIRB - Late Phase Emphasis Completed
E1208 ECOG A Phase III Randomized; Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion Adult CIRB - Late Phase Emphasis Available to Open
S1605 SWOG Phase II Trial of Atezolizumab in BCG-Unresponsive Non-Muscle Invasive Bladder Cancer Adult CIRB - Late Phase Emphasis Available to Open
NRG-GY005 NRG A Randomized Phase II/III study of the combination of Cediranib and Olaparib compared to Cediranib or Olaparib alone; or Standard of care chemotherapy in women with recurrent platinum-resistant or -refractory ovarian; fallopian tube; or primary peritoneal cancer (COCOS) Adult CIRB - Late Phase Emphasis Available to Open
E5508 ECOG Randomized Phase III Study of Maintenance Therapy with Bevacizumab; Pemetrexed; or a Combination of Bevacizumab and Pemetrexed Following Carboplatin; Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC Adult CIRB - Late Phase Emphasis Available to Open
EA6174 ECOG-ACRIN A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma Adult CIRB - Late Phase Emphasis Available to Open
A021502 Alliance Randomized Trial of FOLFOX Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability (ATOMIC*) Adult CIRB - Late Phase Emphasis Available to Open
E3201 ECOG Intergroup Randomized Phase III Study of Postoperative Irinotecan; 5-Fluorouracil and Leucovorin Vs Oxaliplatin; 5-Fluorouracil and Leucovorin Vs 5-Fluorouracil and Leucovorin For Patients with Stage II or III Rectal Cancer Receiving Either Preoperative Radiation and 5-Fluorouracil or Postoperative Radiation and 5-Fluorouracil Adult CIRB - Late Phase Emphasis Completed
GOG-0275 GOG A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia Adult CIRB - Late Phase Emphasis Available to Open
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