CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 31 - 40 of 842
Study Number Lead Group Study Title CIRB Study Status
NRG-CC008 NRG A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk] Cancer Prevention and Control CIRB Available to Open
10015 ETCTN A Non-Randomized; Open-Label; Phase 2 Study of Trametinib in Patients with Unresectable or Metastatic Epithelioid Hemangioendothelioma Adult CIRB - Early Phase Emphasis Available to Open
PBTC-053 PBTC A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma Pediatric CIRB Available to Open
ADVL06B1 COG A Pharmacokinetic-Pharmacodynamic-Pharmacogenetic Study of Actinomycin-D and Vincristine in Children with Cancer: A Group-Wide Non-Therapeutic Study Pediatric CIRB Completed
10066 ETCTN A Phase 1 / 2 Study of Olaparib in Combination with Ramucirumab in Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma Adult CIRB - Early Phase Emphasis Available to Open
10076 ETCTN A Phase 1 Dose-Escalation and Exploratory Dose Expansion Study of KRT-232 (AMG 232) in Combination with Carfilzomib, Lenalidomide, and Dexamethasone in Relapsed and/or Refractory Myeloma. Adult CIRB - Early Phase Emphasis Available to Open
9844 ETCTN A Phase 1 Study Evaluating Safety; Tolerability; and Preliminary Antitumor Activity of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors Adult CIRB - Early Phase Emphasis Available to Open
ADVL1514 COG A Phase 1 Study of ABI-009 (nab-Rapamycin) (IND# 133537) in Pediatric Patients with Recurrent or Refractory Solid Tumors, Including CNS Tumors as a Single Agent and in Combination with Temozolomide and Irinotecan Pediatric CIRB Available to Open
9824 ETCTN A Phase 1 Study of alisertib (MLN8237) in combination with mFOLFOX in gastrointestinal tumors Adult CIRB - Early Phase Emphasis Completed
9853 ETCTN A Phase 1 Study of AZD1775 in Combination with Belinostat in Relapsed and Refractory Myeloid Malignancies and Selected Untreated Patients with Acute Myeloid Leukemia Adult CIRB - Early Phase Emphasis Available to Open
Displaying 31 - 40 of 842