Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|UAZ2015-05-01||CLO-University of Arizona||A prospective, single-arm, open-label, non-randomized, phase IIA trial of a nonavalent prophylactic HPV vaccine to assess immunogenicity of a prime and deferred-booster dosing schedule among 9-11 year-old girls and boys||Cancer Prevention and Control CIRB||Available to Open|
|UAZ2015-05-02||CLO-University of Arizona||M4OC-Prevent: Metformin for Oral Cancer Prevention||Cancer Prevention and Control CIRB||Available to Open|
|UWI2015-05-01||CLO-University of Wisconsin||Phase Ib 9cUAB30 in Early Stage Breast Cancer to Evaluate Biologic Effect||Cancer Prevention and Control CIRB||Available to Open|
|UWI2014-03-01||CLO-University of Wisconsin||A Phase I Trial of the Safety and Immunogenicity of a DNA Plasmid Based Vaccine (WOKVAC) Encoding Epitopes Derived from Three Breast Cancer Antigens (IGFBP-2, HER2, AND IGF-1R) in Patients with Breast Cancer||Cancer Prevention and Control CIRB||Available to Open|
|UWI2016-07-01||CLO-University of Wisconsin||Phase IIB Randomized, Placebo-Controlled Trial of ACTOplus met® XR in Subjects with Stage I-IV Squamous Cell Carcinoma of the Oral Cavity or Oropharynx Prior to Definitive Treatment||Cancer Prevention and Control CIRB||Available to Open|
|UWI2016-08-01||CLO-University of Wisconsin||Pilot Study of Daily Exemestane in Women with Complex Atypical Hyperplasia of the Endometrium / Endometrial Intraepithelial Neoplasia or Grade 1 Endometrial Cancer||Cancer Prevention and Control CIRB||Available to Open|
|PBTC-056||PBTC||A Phase I study of the ADAM-10 inhibitor, INCB7839 in children with recurrent/progressive high-grade gliomas to target microenvironmental neuroligin-3||Pediatric CIRB||Available to Open|
|PBTC-051||PBTC||Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma||Pediatric CIRB||Available to Open|
|PBTC-055||PBTC||Phase I/II trial of Dabrafenib, Trametinib, and Hydroxychloroquine (HCQ) for BRAF V600E-mutant or Trametinib and HCQ for BRAF fusion/duplication positive or NF1-associated recurrent or progressive gliomas in children and young adults||Pediatric CIRB||Available to Open|
|PBTC-049||PBTC||A Phase I study of Savolitinib in Recurrent, Progressive or Refractory Medulloblastoma, High-Grade Glioma, Diffuse Intrinsic Pontine Glioma and CNS tumors harboring MET aberrations||Pediatric CIRB||Available to Open|