CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 821 - 830 of 842
Study Number Lead Group Study Title CIRB Study Status
S1500 SWOG A Randomized; Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968]; Crizotinib [NSC #749005]; Savolitinib [NSC #785348]; and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET) Adult CIRB - Late Phase Emphasis Available to Open
AAML0431 COG The Treatment of Down Syndrome Children with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Under the Age of 4 Years: A Groupwide Phase III Study Pediatric CIRB Available to Open
10042 ETCTN A Phase II trial of AZD9291 (osimertinib) with or without bevacizumab in patients with EGFR mutation positive NSCLC and brain metastases Adult CIRB - Early Phase Emphasis Available to Open
A221504 Alliance A Randomized, Double-Blind, Placebo-Controlled Pilot Study of an Oral, Selective Peripheral Opioid Receptor Antagonist in Advanced Non-Small Cell Lung Cancer Cancer Prevention and Control CIRB Available to Open
AGCT1532 COG Phase 3 Accelerated BEP Trial: A randomized phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumors Pediatric CIRB Available to Open
E1912 ECOG A Randomized Phase III Study of Ibrutinib (PCI- 32765)-based Therapy vs Standard Fludarabine; Cyclophosphamide; and Rituximab (FCR) Chemoimmunotherapy in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL) Adult CIRB - Late Phase Emphasis Available to Open
A041701 Alliance A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy Adult CIRB - Late Phase Emphasis Available to Open
PACCT-1 ECOG Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial Adult CIRB - Late Phase Emphasis Available to Open
ACNS1833 COG A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1) Pediatric CIRB Available to Open
GOG-0261 GOG A Randomized Phase III Trial of Paclitaxel Plus Carboplatin Versus Ifosfamide Plus Paclitaxel in Chemotherapy-Naive Patients with Newly Diagnosed Stage I-IV; Persistent or Recurrent Carcinosarcoma (Mixed Mesodermal Tumors) of the Uterus; Fallopian Tube; Peritoneum or Ovary Adult CIRB - Late Phase Emphasis Available to Open
Displaying 821 - 830 of 842