CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 21 - 30 of 867
Study Number Lead Group Study Title CIRB Study Status
A031501 Alliance Phase III Randomized Adjuvant Study of MK-3475 (Pembrolizumab) in Muscle Invasive and Locally Advanced Urothelial Carcinoma (Ambassador) Versus Observation Adult CIRB - Late Phase Emphasis Available to Open
10139 ETCTN A Randomized Phase 2 Study of Atezolizumab in Combination with Cobimetinib versus Atezolizumab Monotherapy in Participants with Unresectable Cholangiocarcinoma Adult CIRB - Early Phase Emphasis Available to Open
MAY2017-09-01 CLO-Mayo Clinic Phase I Double-Blind, Placebo-Controlled Trial of 27 mg Dolcanatide (SP-333) to Demonstrate Colorectal Bioactivity in Healthy Volunteers Cancer Prevention and Control CIRB Available to Open
AAML1031 COG A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239; NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD Pediatric CIRB Available to Open
10147 ETCTN A Phase II randomized study of topotecan/carboplatin with or without veliparib in advanced myeloproliferative disorders and chronic myelomonocytic leukemia (CMML). Adult CIRB - Early Phase Emphasis Available to Open
ALTE11C1 COG Longitudinal Assessment of Ovarian Reserve in Adolescents with Lymphoma: A Groupwide Non-Therapeutic Protocol Pediatric CIRB Available to Open
RTOG-0815 RTOG A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
A091401 Alliance Randomized Phase II Study Of Nivolumab With Or Without Ipilimumab In Patients With Metastatic Or Unresectable Sarcoma Adult CIRB - Late Phase Emphasis Available to Open
10296 ETCTN Phase Ib/II trial of copanlisib in combination with trastuzumab and pertuzumab after induction treatment of HER2 positive (HER2+) metastatic breast cancer (MBC) with PIK3CA mutation or PTEN mutation Adult CIRB - Early Phase Emphasis Available to Open
A031901 Alliance Duration of Immune Checkpoint Therapy in Locally Advanced or Metastatic Urothelial Carcinoma: A Randomized Phase 3 Non-Inferiority Trial Adult CIRB - Late Phase Emphasis Available to Open
Displaying 21 - 30 of 867