Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|S1400ANCILLARY||SWOG||Ancillary Study to Evaluate Patient and Physician Attitudes; Knowledge; and Expectations Related to Return of Genomic Results in Cancer in the SWOG 1400 (S1400) Clinical Trial||Adult CIRB - Late Phase Emphasis|
|E1A06||ECOG||An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan; Prednisone and Thalidomide (MPT) Versus Melphalan; Prednisone and Lenalidomide (Revlimid TM) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|A091304||Alliance||A Phase I /Randomized Phase II Study of MLN0128 vs. Pazopanib In Patients With Locally Advanced/Unresectable And/Or Metastatic Sarcoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|S1501||SWOG||Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer; Phase III||Cancer Prevention and Control CIRB||Available to Open|
|MDA2017-09-03||CLO-MD Anderson||Pilot Study of Denosumab in BRCA1/2 Mutation Carriers scheduled for Risk-reducing Salpingooophorectomy||Cancer Prevention and Control CIRB||Available to Open|
|AHOD03P1||COG||Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study||Pediatric CIRB||Available to Open|
|NSABP-B-42||NSABP||A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Postmenopausal Women with Hormone Receptor Positive Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|UWI2015-05-01||CLO-University of Wisconsin||Phase Ib 9cUAB30 in Early Stage Breast Cancer to Evaluate Biologic Effect||Cancer Prevention and Control CIRB||Available to Open|
|EA6174||ECOG-ACRIN||A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|PBTC-056||PBTC||A Phase I study of the ADAM-10 inhibitor, INCB7839 in children with recurrent/progressive high-grade gliomas to target microenvironmental neuroligin-3||Pediatric CIRB||Available to Open|