CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 830
Study Number Lead Group Study Title CIRB Study Status
PEPN1812 A Phase 1 Trial of the CD123 X CD3 Dual Affinity Re-Targeting Antibody Flotetuzumab (NSC#808294, IND #145986) in Children, Adolescents, and Young Adults with Relapsed or Refractory Acute Myeloid Leukemia Pediatric CIRB Available to Open
ACOSOG-Z1031 ACSOG A Randomized Phase III Trial Comparing 16 to 18 Weeks of Neoadjuvant Exemestane (25 mg daily); Letrozole (2.5 mg); or Anastrozole (1 mg) in Postmenopausal Women with Clinical Stage II and III Estrogen Receptor Positive Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z1041 ACSOG A Randomized Phase III Trial Comparing a Neoadjuvant Regimen of FEC-75 Followed by Paclitaxel Plus Trastuzumab With a Neoadjuvant Regimen of Paclitaxel Plus Trastuzumab Followed by FEC-75 Plus Trastuzumab in Patients with HER-2 Positive Operable Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z4032 ACSOG A Randomized Phase III Study of Sublobar Resection versus Sublobar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC); 3 cm or Smaller Adult CIRB - Late Phase Emphasis Completed
ACOSOG-Z4099 ACSOG A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)<br><br> Adult CIRB - Late Phase Emphasis Completed
ACOSOG-Z6051 ACSOG A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z9031 ACSOG A Phase III Randomized Study of Preoperative Radiation Plus Surgery Versus Surgery Alone for Patients with Retroperitoneal Sarcomas (RPS) Adult CIRB - Late Phase Emphasis Completed
A211601 Alliance Evaluation of Mammographic Breast Density Effect of Aspirin: A companion study to Alliance Study A011502 Cancer Prevention and Control CIRB Available to Open
A041701 Alliance A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy Adult CIRB - Late Phase Emphasis Available to Open
A021502 Alliance Randomized Trial of FOLFOX Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability (ATOMIC*) Adult CIRB - Late Phase Emphasis Available to Open
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