Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|S0023||SWOG||A Phase III Trial of Cisplatin/Etoposide/ Radiotherapy with Consolidation Docetaxel Followed by Maintenance Therapy with ZD1839 or Placebo in Patients with Inoperable Locally Advanced Stage III Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|ACNS0221||COG||A Phase II Study of Conformal Radiotherapy In Patients with Low-Grade Gliomas||Pediatric CIRB||Completed|
|S0502||SWOG||A Phase III Randomized Study of Imatinib; with or without Bevacizumab (NSC-704865); in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors NCT #00324987||Adult CIRB - Late Phase Emphasis||Completed|
|E2212||ECOG||A Randomized; Double-Blinded; Placebo-Controlled Phase II Study of Adjuvant Everolimus Following the Resection of Metastatic Pancreatic Neuroendocrine Tumors to the Liver||Adult CIRB - Early Phase Emphasis||Completed|
|ADVL0524||COG||Phase II Trial of Ixabepilone (BMS-247550); an Epothilone B Analog; in Children and Young Adults with Refractory Solid Tumors||Pediatric CIRB||Completed|
|NSABP-C-09||NSABP||A Phase III Clinical Trial Comparing Oxaliplatin; Capecitabine; and Hepatic Arterial Infusion of Floxuridine to Oxaliplatin and Capecitabine in Patients with Resected or Ablated Liver Metastases from Colorectal Cancer.||Adult CIRB - Late Phase Emphasis||Completed|
|GOG-0219||GOG||A Phase III; Randomized Trial of Weekly Cisplatin and Radiation Versus Cisplatin and Tirapazamine and Radiation in Stage IB2; IIA; IIB; IIIB; and IVA Cervical Carcinoma Limited to the Pelvis||Adult CIRB - Late Phase Emphasis||Completed|
|AEWS0521||COG||A Randomized Phase II Study of Bevacizumab (NSC 704865; BB-IND# 7921) Combined with Vincristine; Topotecan and Cyclophosphamide in Patients with First Recurrent Ewing Sarcoma||Pediatric CIRB||Completed|
|N0723||NCCTG||MARVEL: Marker Validation of Erlotinib in Lung Cancer- A Phase III Biomarker Validation Study of Second-line Therapy in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Randomized to Pemetrexed Versus Erlotinib||Adult CIRB - Late Phase Emphasis||Completed|
|RTOG-0421||RTOG||A Phase III Trial for Locally Recurrent; Previously Irradiated Head and Neck Cancer: Concurrent Re-Irradiation and Chemotherapy Versus Chemotherapy Alone.||Adult CIRB - Late Phase Emphasis||Completed|