Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|A151216||Alliance||Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)||Adult CIRB - Late Phase Emphasis||Available to Open|
|A031102||Alliance||A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel; Ifosfamide; and Cisplatin (TIP) with High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors||Adult CIRB - Late Phase Emphasis||Available to Open|
|A211601||Alliance||Evaluation of Mammographic Breast Density Effect of Aspirin: A companion study to Alliance Study A011502||Cancer Prevention and Control CIRB||Available to Open|
|A091603||Alliance||A Randomized Phase II Trial of Adjuvant Nivolumab or Expectant Observation Following Neoadjuvant Ipilimumab Plus Nivolumab and Surgical Resection of High-Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma||Adult CIRB - Late Phase Emphasis||Completed|
|A011202||Alliance||A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|A211701||Alliance||A Prospective Study to Establish a New Onset Hyperglycemia and Diabetes (NOD) Cohort||Cancer Prevention and Control CIRB||Available to Open|
|A091902||Alliance||A Multicenter Phase II Trial of Paclitaxel with and without Nivolumab in Taxane Naive, and Nivolumab and Cabozantinib in Taxane Pretreated Subjects with Angiosarcoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|A071701||Alliance||Genomically-Guided Treatment Trial in Brain Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|A071401||Alliance||Phase II Trial of SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas with SMO/AKT/NF2/CDK Pathway Mutations||Adult CIRB - Early Phase Emphasis||Available to Open|
|A031201||Alliance||Phase III Trial of Enzalutamide (NSC # 766085) Versus Enzalutamide; Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|