Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NRG-GY017||NRG||Anti PD-L1 (Atezolizumab) as an Immune Primer and Concurrently with Extended Field Chemoradiotherapy for Node Positive Locally Advanced Cervical Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|10020||ETCTN||A Phase II Open-Label, Randomized Study of PARP Inhibition (olaparib) Either Alone or in Combination with Anti-PD-L1 Therapy (atezolizumab; MPDL3280A) in Homologous DNA Repair (HDR) Deficient, Locally Advanced or Metastatic Non-HER2-positive Breast Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|ARAR0331||COG||Treatment of Childhood Nasopharyngeal Carcinoma with Neoadjuvant Chemotherapy and Concomitant Chemoradiotherapy: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|E2805||ECOG||ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-GU008||NRG||Randomized Phase III Trial Incorporating Abiraterone Acetate with Prednisone and Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer after Radical Prostatectomy||Adult CIRB - Late Phase Emphasis||Available to Open|
|WF-1805CD||NCORP-Wake Forest University||Implementation and Effectiveness Trial of HN-STAR||Cancer Prevention and Control CIRB||Available to Open|
|10067||ETCTN||A randomized phase 2 trial of cediranib and olaparib compared to bevacizumab in patients with recurrent glioblastoma who have not received prior VEGF therapy||Adult CIRB - Early Phase Emphasis||Available to Open|
|10104||ETCTN||A Randomized Phase 2 Study of Cabozantinib in Combination with Nivolumab in Advanced, Recurrent Metastatic Endometrial Cancer.||Adult CIRB - Early Phase Emphasis||Available to Open|
|AHOD03P1||COG||Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study||Pediatric CIRB||Available to Open|
|9914||ETCTN||A Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|