Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|MDA2016-08-02||CLO-MD Anderson||A Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer||Cancer Prevention and Control CIRB||Available to Open|
|NRG-GI005||NRG||Phase II/III Study of Circulating tumOr DNA as a Predictive BiomaRker in Adjuvant Chemotherapy in Patients with Stage IIA Colon Cancer (COBRA)||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1400||SWOG||A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-Map)||Adult CIRB - Late Phase Emphasis||Available to Open|
|E2108||ECOG||A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|10366||ETCTN||A Phase 1/2 Study of M3814 (peposertib) in Combination with Hypofractionated Radiotherapy for the Treatment of Locally Advanced Pancreatic Adenocarcinoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|NRG-HN004||NRG||Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-90203||CALGB||A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk; Clinically Localized Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|10150||ETCTN||A randomized phase 2 study of bevacizumab and either weekly anetumab ravtansine or weekly paclitaxel in platinum-resistant or platinum refractory ovarian cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|9892||ETCTN||Phase I Dose-Escalation Bioavailability Study of Oral Triapine in Combination with Concurrent Chemoradiation for Locally Advanced Cervical Cancer (LACC) and Vulvar Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|ANBL00P3||COG||A Phase III Randomized Trial of Intravenous Gammaglobulin Therapy for Patients with Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated with Chemotherapy and Prednisone||Pediatric CIRB||Available to Open|