Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NRG-GI001||NRG||Randomized Phase III Study of Focal Radiation Therapy for Unresectable; Localized Intrahepatic Cholangiocarcinoma||Adult CIRB - Late Phase Emphasis||Completed|
|A071102||Alliance||A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1826||SWOG||A Phase III, Randomized Study of Nivolumab (Opdivo) plus AVD or Brentuximab Vedotin (Adcetris) plus AVD in Patient (Age >/= 12 Year) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|E5103||ECOG||A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide Followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0502||SWOG||A Phase III Randomized Study of Imatinib; with or without Bevacizumab (NSC-704865); in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors NCT #00324987||Adult CIRB - Late Phase Emphasis||Completed|
|NRG-GI004||NRG||Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with or without Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients with Deficient DNA Mismatch Repair (dMMR) Metastatic Colorectal Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|E1900||ECOG||A Phase III Trial in Adult Acute Myeloid Leukemia: Daunorubicin Dose-<br>Intensification Prior to Risk-Allocated Autologous Stem Cell Transplantation||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1937||SWOG||A Phase III Randomized Trial of Eribulin (NSC #707389) with or without Gemcitabine versus Standard of Care (Physician's Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible for, Anti PD1/PDL1 Therapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|N107C||NCCTG||A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-40601||CALGB||Randomized Phase III Trial of Paclitaxel + Trastuzumab + Lapatinib Versus Paclitaxel + Trastuzumab as Neoadjuvant Treatment of HER2-Positive Primary Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|