Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|E4A08||ECOG||A Randomized Phase III Trial of Melphalan and Dexamethasone (MDex) versus Bortezomib; Melphalan; and Dexamethasone (BMDex) for Untreated Patients with Systemic Light-chain (AL) Amyloidosis Ineligible for Autologous Stem-cell Transplantation||Adult CIRB - Late Phase Emphasis||Completed|
|CCTG MA.39||NCIC CTG||Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|ABTC-1802||ABTC||A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor||Adult CIRB - Late Phase Emphasis||Available to Open|
|E1A06||ECOG||An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan; Prednisone and Thalidomide (MPT) Versus Melphalan; Prednisone and Lenalidomide (Revlimid TM) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA5152||ECOG-ACRIN||A Randomized Phase II Trial of Nivolumab, Cabozantinib Plus Nivolumab, and Cabozantinib Plus Nivolumab Plus Ipilimumab in Patients with Previously Treated Non-Squamous NSCLC||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-HN002||NRG||A Randomized Phase II Trial for Patients with p16 Positive; Non-Smoking Associated; Locoregionally Advanced Oropharyngeal Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0534||RTOG||A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA after Radical Prostatectomy||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1706||SWOG||A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|GOG-0275||GOG||A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia||Adult CIRB - Late Phase Emphasis||Available to Open|
|S1216||SWOG||A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|