CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 546
Study Numbersort descending Lead Group Study Title CIRB Study Status
S1616 SWOG A Phase II Randomized Study of Nivolumab (NSC-748726) with Ipilimumab (NSC-732442) or Ipilimumab Alone in Advanced Melanoma Patients Refractory to an Anti-PD1 or Anti-PD-L1 Agent Adult CIRB - Late Phase Emphasis Available to Open
10005 ETCTN A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Alveolar Soft Part Sarcoma Adult CIRB - Early Phase Emphasis Available to Open
10009 ETCTN A Phase 1b study of the anti-PD1 antibody Pembrolizumab in combination with the histone deacetylase inhibitor; Entinostat for treatment of patients with myelodysplastic syndromes after DNA methyltransferase inhibitor therapy failure Adult CIRB - Early Phase Emphasis Available to Open
10010 ETCTN A Phase 2 Study of Atezolizumab (MPDL3280A) in Combination with Bevacizumab in Patients with Recurrent; Persistent or Metastatic Cervical Cancer Adult CIRB - Early Phase Emphasis Available to Open
10013 ETCTN Randomized Phase 2 Study of Neoadjuvant Chemotherapy; Carboplatin and Paclitaxel; with or without Atezolizumab in Triple Negative Breast Cancer (TNBC) Adult CIRB - Early Phase Emphasis
10014 ETCTN A Pilot Study of Atezolizumab (MPDL3280A) Following Adoptive Cell Transfer in Active Hematologic or Solid Tumor Malignancies Adult CIRB - Early Phase Emphasis Available to Open
10015 ETCTN A Non-Randomized; Open-Label; Phase 2 Study of Trametinib in Patients with Unresectable or Metastatic Epithelioid Hemangioendothelioma Adult CIRB - Early Phase Emphasis Available to Open
10020 ETCTN A Phase II Multiple-Arm; Open-Label; Randomized Study of PARP inhibition (veliparib; ABT-888) and Anti-PD-L1 Therapy (atezolizumab; MPDL3280A) Either alone or in Combination in Homologous DNA Repair (HDR) Deficient Triple Negative Breast Cancer (TNBC) Adult CIRB - Early Phase Emphasis Available to Open
10021 ETCTN A Phase 2 Study of MEDI4736(durvalumab) and Tremelimumab Alone or in Combination with High or Low-Dose Radiation in Metastatic Colorectal and NSCLC Adult CIRB - Early Phase Emphasis Available to Open
10026 ETCTN A Phase 1 Study of Ipilimumab in Combination with Decitabine in Relapsed or Refractory Myelodysplastic Syndrome/Acute Myeloid Adult CIRB - Early Phase Emphasis Available to Open
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