CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

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Study Number Lead Group Study Title CIRB Study Status
RTOG-0214 RTOG A Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non-Small Cell Lung Cancer Adult CIRB - Late Phase Emphasis Completed
RTOG-0724 RTOG Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy Adult CIRB - Late Phase Emphasis Available to Open
RTOG-0521 RTOG A Phase III Protocol of Androgen Suppression (AS) and 3DCRT/IMRT vs. AS and 3DCRT/IMRT followed by Chemotherapy with Docetaxel and Prednisone for Localized; High-Risk Prostate Cancer Adult CIRB - Late Phase Emphasis Completed
RTOG-BR-0118 RTOG A Phase III Study of Conventional Radiation Therapy Plus Thalidomide (NSC# 66847) Versus Conventional Radiation Therapy For Multiple Brain Metastases Adult CIRB - Late Phase Emphasis Completed
RTOG-1010 RTOG A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma Adult CIRB - Late Phase Emphasis Completed
RTOG-0232 RTOG A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy Alone for Selected Patients with Intermediate Risk Prostatic Carcinoma Adult CIRB - Late Phase Emphasis Completed
RTOG-0815 RTOG A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
S1900K RTOG A Randomized Phase II Study of Tepotinib with or without Ramucirumab in Participants with MET Exon 14 Skipping Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study) Adult CIRB - Late Phase Emphasis Available to Open
RTOG-P-0011 RTOG Phase III Randomized Study of Adjuvant Therapy For High Risk PT2-3N0 Prostate Cancer Adult CIRB - Late Phase Emphasis Completed
RTOG-1016 RTOG Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer Adult CIRB - Late Phase Emphasis Available to Open
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