CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
Study Number | Lead Group | Study Title | CIRB | Study Status |
---|---|---|---|---|
ADVL0525 | COG | A Phase II Study of Pemetrexed in Children with Recurrent Malignancies | Pediatric CIRB | Completed |
PBTC-060 | PBTC | A Pilot Study of Safety, Tolerability, and Immunological Effects of SurVaxM in Pediatric Patients with Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma | Pediatric CIRB | Available to Open |
ALTE11C2 | COG | Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy: A Limited Institution Non-Therapeutic Study | Pediatric CIRB | Available to Open |
ARET2121 | COG | Intravitreal Melphalan for Intraocular Retinoblastoma | Pediatric CIRB | Available to Open |
ACNS0222 | COG | A Phase II Study of Motexafin-Gadolinium (NSC #695238; IND #55583) and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Groupwide Phase II Study | Pediatric CIRB | Completed |
AALL1631 | COG | International Phase 3 trial in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) testing imatinib in combination with two different cytotoxic chemotherapy backbones | Pediatric CIRB | Available to Open |
AEWS0521 | COG | A Randomized Phase II Study of Bevacizumab (NSC 704865; BB-IND# 7921) Combined with Vincristine; Topotecan and Cyclophosphamide in Patients with First Recurrent Ewing Sarcoma | Pediatric CIRB | Completed |
ADVL1712 | COG | A Feasibility Trial of MLN4924 (Pevonedistat, TAK 924, IND#142772) Given in Combination with Azacitidine, Fludarabine, and Cytarabine, in Children, Adolescents, and Young Adults with Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome | Pediatric CIRB | Available to Open |
ACCL16N1CD | COG | Documentation and Delivery of Guideline-Consistent Treatment in Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL) | Pediatric CIRB | Available to Open |
ANBL12P1 | COG | Pilot Study Using Myeloablative Busulfan/Melphalan (BuMel) Consolidation Following Induction Chemotherapy for Patients with Newly Diagnosed High-Risk Neuroblastoma | Pediatric CIRB | Available to Open |