CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 10466 | ETCTN | A Phase 2 Study of Bevacizumab, Erlotinib and Atezolizumab in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Associated or Sporadic Papillary Renal Cell Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| ACCL20N1CD | COG | Financial Distress during Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States | Pediatric CIRB | Available to Open |
| S1607 | SWOG | A Phase II Study of Combining Talimogene Laherparepvec (T-VEC) (NSC-785349) and MK-3475 (Pembrolizumab) (NSC-776864) in Patients with Advanced Melanoma who have Progressed on ANTI-PD1/L1 Based Therapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| EAA173 | ECOG-ACRIN | Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A221208 | Alliance | Randomized Phase II Study: Corticosteroids and Bevacizumab vs. Corticosteroids and Placebo (BeSt) for Radionecrosis after Radiosurgery for Brain Metastases | Cancer Prevention and Control CIRB | Available to Open |
| EA5152 | ECOG-ACRIN | A Randomized Phase II Trial of Nivolumab, Cabozantinib Plus Nivolumab, and Cabozantinib Plus Nivolumab Plus Ipilimumab in Patients with Previously Treated Non-Squamous NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |
| A031803 | Alliance | Phase II Trial of Intravesical Gemcitabine and MK-3475 (pembrolizumab) in the Treatment of Patients with BCG-Unresponsive Non-Muscle Invasive Bladder Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A021806 | Alliance | A Phase III Trial of Perioperative versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| ACCL1633 | COG | The Effectiveness of Lactobacillus plantarum (LBP, IND #17339) In preventing Acute Graft-versus-Host Disease (GvHD) in Children undergoing Alternative Hematopoietic Progenitor Cell Transplantation (HCT) | Pediatric CIRB | Available to Open |
| S1820 | SWOG | A Randomized Trial of the Altering Intake, Managing Symptoms Intervention for Bowel Dysfunction in Rectal Cancer Survivors Compared to a Healthy Living Education Control: A Feasibility and Preliminary Efficacy Study (AIMS-RC) | Cancer Prevention and Control CIRB | Available to Open |