CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ACCRN07 | COG | Protocol for the Enrollment on the Official COG Registry; The Childhood Cancer Research Network (CCRN) | Pediatric CIRB | Available to Open |
| 9979 | ETCTN | Phase 1 and Pharmacology Study of Oral 5-iodo-2-pyrimidinone-2-deoxyribose (IPdR) as a Prodrug for IUdR-Mediated Tumor Radiosensitization in Brain Metastases | Adult CIRB - Early Phase Emphasis | Available to Open |
| EA2197 | ECOG-ACRIN | Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-BR007 | NRG | A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER2-Negative, Oncotype Recurrence Score ≤18 Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1612 | SWOG | A Randomized Phase II/III Trial of "Novel Therapeutics" versus Azacitidine in Newly Diagnosed Patients with Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS), Age 60 or Older | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-LU005 | NRG | Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab | Adult CIRB - Late Phase Emphasis | Available to Open |
| A092107 | Alliance | A Randomized Phase 2 Trial with a Safety Lead-In to Evaluate Palbociclib versus Palbociclib and Cemiplimab for the Treatment of Advanced Dedifferentiated Liposarcoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| ABTC-1604 | Alliance | Phase 0/I Study of AMG 232 (KRT 232) Concentrations in Brain Tissue in Patients with Recurrent Glioblastoma and of AMG 232 (KRT 232) in Combination with Radiation in Patients with Newly Diagnosed Glioblastoma and Unmethylated MGMT Promoters | Adult CIRB - Late Phase Emphasis | Available to Open |
| WF-2300CD | NCORP-Wake Forest University | Practice Survey for Multi-site Community Oncology Planning for the CONNECT Intervention Targeting Lung Cancer Caregivers | Cancer Prevention and Control CIRB | Available to Open |
| 10327 | ETCTN | A Phase 1 Trial of MLN0128 (sapanisertib) and CB-839 HCl (telaglenastat) in Advanced NSCLC Patients | Adult CIRB - Early Phase Emphasis | Available to Open |