CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A021502 | Alliance | Randomized Trial of Standard Chemotherapy Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair (ATOMIC: Adjuvant Trial of Deficient Mismatch Repair in Colon Cancer) | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10015 | ETCTN | A Non-Randomized; Open-Label; Phase 2 Study of Trametinib in Patients with Unresectable or Metastatic Epithelioid Hemangioendothelioma | Adult CIRB - Early Phase Emphasis | Available to Open |
| ARET2121 | COG | Intravitreal Melphalan for Intraocular Retinoblastoma | Pediatric CIRB | Available to Open |
| S1900A | SWOG | A Phase II Study of Rucaparib in Patients with Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-Small Cell Lung Cancer (LungMAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10487 | ETCTN | A Phase II study of Lutetium Lu 177 dotatate in metastatic prostate cancer with neuroendocrine differentiation | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-GI006 | NRG | Phase III Randomized Trial of Proton Beam Therapy (PBT) versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| WF-97116 | NCORP-Wake Forest University | A Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil in Chemotherapy Exposed Breast Cancer Survivors with Cognitive Impairment (REMEMBER) | Cancer Prevention and Control CIRB | Available to Open |
| NSABP-B-51 | NSABP | A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY019 | NRG | A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole Versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10061 | ETCTN | A Phase 1 Study of MK-3475 (Pembrolizumab) in Combination with Recombinant Interleukin-12 in Patients with Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open |