CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| AREN0321 | COG | Treatment of High Risk Renal Tumors: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| EA1141 | ECOG-ACRIN | Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis in Breast Cancer Screening in Women with Dense Breasts | Cancer Prevention and Control CIRB | Completed |
| ACCL1031 | COG | A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| S0205 | SWOG | A Phase III Randomized Open-Label Study Comparing Gemcitabine Plus Cetuximab (IMC-C225) Versus Gemcitabine as First-Line Therapy of Patients with Advanced Pancreas Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| CALGB-90401 | CALGB | A Randomized Double-Blinded Placebo Controlled Phase III Trial Comparing Docetaxel and Prednisone with and without Bevacizumab (IND #7921; NSC #704865) in Men with Hormone Refractory Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-0232 | RTOG | A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy with Brachytherapy Alone for Selected Patients with Intermediate Risk Prostatic Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| ACNS1021 | COG | A Phase II Study of Sunitinib (NSC# 736511; IND# 74019) in Recurrent; Refractory or Progressive High Grade Glioma and Ependymoma Tumors in Pediatric and Young Adult Patients | Pediatric CIRB | Completed |
| S0012 | SWOG | A Comparative Randomized Study of Standard Doxorubicin and Cyclophosphamide Followed by Weekly Paclitaxel Vs. Weekly Doxorubicin and Daily Oral Cyclophosphamide Plus G-CSF Followed by Weekly Paclitaxel as Neoadjuvant Therapy for Inflammatory and Locally Advanced Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ARST0531 | COG | Randomized Study of Vincristine; Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS): A Groupwide Phase III Study | Pediatric CIRB | Completed |
| EAQ152 | ECOG-ACRIN | A Randomized Study of Pre-disclosure Genetic Education v. Usual Care in Tumor Profiling for Advanced Cancer and a Pilot Study of Remote Genetic Counseling for Participants with Potential Germline Mutations Identified on Tumor Profiling | Adult CIRB - Early Phase Emphasis | Completed |