CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ARST0921 | COG | A Randomized Phase II Trial of Bevacizumab (IND# 7921; Avastin) and Temsirolimus (IND# 61010; Torisel) in Combination with Intravenous Vinorelbine and Cyclophosphamide in Patients with Recurrent/Refractory Rhabdomyosarcoma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| NSABP-R-04 | NSABP | A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with or without Oxaliplatin with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-Fluorouracil with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma of the Rectum | Adult CIRB - Late Phase Emphasis | Completed |
| A021302 | Alliance | Impact of Early FDG-PET Directed Intervention on Preoperative Therapy for Locally Advanced Gastric Cancer: A Random Assignment Phase II Study | Adult CIRB - Early Phase Emphasis | Completed |
| ADVL1315 | COG | A Phase 1 Study of the VEGF Receptor Tyrosine Kinase Inhibitor Axitinib (INLYTA; 123101) in Children with Recurrent or Refractory Solid Tumors | Pediatric CIRB | Completed |
| NRG-GY011 | NRG | A Randomized Surgical Window Pilot Investigation of the Relationship of Short Term Medroxyprogesterone Acetate (NSC #26386) Compared to Medroxyprogesterone Acetate Plus Entinostat (NSC #706995) on the Morphologic, Biochemical, and Molecular Changes in Primary Endometrioid Adenocarcinoma of the Uterine Corpus | Adult CIRB - Late Phase Emphasis | Completed |
| A211701 | Alliance | A Prospective Study to Establish a New Onset Hyperglycemia and Diabetes (NOD) Cohort | Cancer Prevention and Control CIRB | Completed |
| EA8141 | ECOG-ACRIN | A Prospective Phase II Trial of Neoadjuvant Systemic Chemotherapy followed by Extirpative Surgery for Patients with High Grade Upper Tract Urothelial Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| 10249 | ETCTN | MLN9708 (Ixazomib) and MLN4924 (Pevonedistat) in Relapsed/Refractory Multiple Myeloma Patients: A Phase 1b Trial | Adult CIRB - Early Phase Emphasis | Completed |
| NSABP-B-33 | NSABP | A Randomized; Placebo-Controlled; Double-Blind Trial Evaluating the Effect of Exemestane in Clinical Stage T1-3N0-1M0 Postmenopausal Breast Cancer Patients Completing at Least Five Years of Tamoxifen Therapy | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-HN007 | NRG | An Open-Label, Phase III Study of Platinum-Gemcitabine with or without Nivolumab in the First-Line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |