CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ADVL0221 | COG | A Phase II Study of Trabectedin (ET-743; Yondelis) in Children with Recurrent Rhabdomyosarcoma; Ewing Sarcoma; or Nonrhabdomyosarcomatous Soft Tissue Sarcomas | Pediatric CIRB | Completed |
| S0518 | SWOG | Phase III Prospective Randomized Comparison of Depot Octreotide plus Interferon Alpha versus Depot Octreotide plus Bevacizumab (NSC #704865) in Advanced; Poor Prognosis Carcinoid Patients | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-BR005 | NRG | A Phase II Trial Assessing the Accuracy of Tumor Bed Biopsies in Predicting Pathologic Response in Patients with Clinical/Radiologic Complete Response after Neoadjuvant Chemotherapy in Order to Explore the Feasibility of Breast Conserving Treatment without Surgery | Adult CIRB - Late Phase Emphasis | Completed |
| AOST06P1 | COG | Feasibility and Dose Discovery Analysis of Zoledronic Acid with Concurrent Chemotherapy in the Treatment of Newly Diagnosed Metastatic Osteosarcoma: A Groupwide Pilot Study | Pediatric CIRB | Completed |
| AAML0523 | COG | A Phase I/II Study of CLOLAR® (Clofarabine, IND# 73,789) in Combination with Cytarabine in Pediatric Patients with Refractory/Relapsed Leukemia | Pediatric CIRB | Completed |
| E1302 | ECOG | Phase III Randomized; Placebo-Controlled Trial of Docetaxel Versus Docetaxel Plus ZD1839 (Iressa; Gefitinib) in Performance Status 2 or Previously Treated Patients with Recurrent or Metastatic Head and Neck Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| NHSR10.2021 | NCI | 21st Century Cures Act and PRA Implementation | Adult CIRB - Late Phase Emphasis | Completed |
| 10010 | ETCTN | A Phase 2 Study of Atezolizumab (MPDL3280A) in Combination with Bevacizumab in Patients with Recurrent; Persistent or Metastatic Cervical Cancer | Adult CIRB - Early Phase Emphasis | Completed |
| NCCTG-N06C6 | NCCTG | A Phase III Randomized Trial of Cryoablation vs. Radiation for the Palliation of Painful Bone Metastases | Adult CIRB - Late Phase Emphasis | Completed |
| ACCL05C1 | COG | A Group-Wide; Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy | Pediatric CIRB | Completed |