CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A231901CD | Alliance | Improving Patient-Centered Communication in Breast Cancer: A RCT of a Shared Decision Engagement System (SHARES) | Cancer Prevention and Control CIRB | Available to Open |
| A041501 | Alliance | A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (A Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) with Newly Diagnosed Precursor B-Cell ALL | Adult CIRB - Late Phase Emphasis | Available to Open |
| A231701CD | Alliance | Increasing Socioeconomically Disadvantaged Patients’ Engagement in Breast Cancer Surgery Decision Making Through a Shared Decision Making Intervention | Cancer Prevention and Control CIRB | Available to Open |
| A091401 | Alliance | Randomized Phase II Study Of Nivolumab With Or Without Ipilimumab In Patients With Metastatic Or Unresectable Sarcoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| A221602 | Alliance | Olanzapine with or without fosaprepitant for the prevention of chemotherapy induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC): A Phase III Randomized, Double Blind, Placebo-Controlled Trial | Cancer Prevention and Control CIRB | Available to Open |
| A071702 | Alliance | A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| A031902 | Alliance | CASPAR - A Phase III Trial of Enzalutamide and Rucaparib as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A022101 | Alliance | A Pragmatic Randomized Phase III Trial Evaluating Total Ablative Therapy for Patients with Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A061402 | Alliance | Solitary Plasmacytoma of Bone: Randomized Phase III Trial to Evaluate Treatment with Adjuvant Systemic Treatment and Zoledronic Acid Versus Zoledronic Acid After Definite Radiation Therapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071701 | Alliance | Genomically-Guided Treatment Trial in Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |