CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| RTOG-0522 | RTOG | A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation; Cisplatin and Cetuximab (C225) [Followed by Surgery for Selected Patients] For Stage III and IV Head and Neck Carcinomas<br> | Adult CIRB - Late Phase Emphasis | Completed |
| S1900B | SWOG | A Phase II Study of LOXO-292 in Patients with RET Fusion-Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (LungMAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |
| E2902 | ECOG | A Phase III Randomized Study of Farnesyl Transferase Inhibitor R115777 in Acute Myeloid Leukemia (AML) Patients in Second or Subsequent Remission or in Remission After Primary Induction Failure or Patients over Age 60 in First Remission | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0219 | GOG | A Phase III; Randomized Trial of Weekly Cisplatin and Radiation Versus Cisplatin and Tirapazamine and Radiation in Stage IB2; IIA; IIB; IIIB; and IVA Cervical Carcinoma Limited to the Pelvis | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0286B | GOG | A Randomized Phase II/III Study Of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo As Initial Therapy For Measurable Stage III Or IVA; Stage IVB; or Recurrent Endometrial Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S0307 | SWOG | Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-B-35 | NSABP | A Clinical Trial Comparing Anastrozole with Tamoxifen in Postmenopausal Patients with Ductal Carcinoma in Situ (DCIS) Undergoing Lumpectomy with Radiation Therapy | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GI003 | NRG | Phase III Randomized Trial of Protons versus Photons for Hepatocellular Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA1181 | ECOG-ACRIN | (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response | Adult CIRB - Late Phase Emphasis | Available to Open |
| A021806 | Alliance | A Phase III Trial of Perioperative versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |