CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

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Study Number Lead Group Study Title CIRB Study Status
ASCT1221 COG A Randomized Phase II Study Comparing Two Different Conditioning Regimens Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Children with Juvenile Myelomonocytic Leukemia (JMML) Pediatric CIRB Completed
AEPI05N1 COG Carcinogen Metabolism; DNA Repair; Parental Exposures and Retinoblastoma: A Groupwide Non-Therapeutic Study Pediatric CIRB Completed
NRG-CC001 NRG A Randomized Phase III Trial Of Memantine And Whole-Brain Radiotherapy With Or Without Hippocampal Avoidance In Patients With Brain Metastases Cancer Prevention and Control CIRB Completed
S0337 SWOG A Phase III Blinded Study of Immediate Post-TURBT Instillation of Gemcitabine Versus Saline in Patients with Newly Diagnosed or Occasionally Recurring Grade I/II Superficial Bladder Cancer Adult CIRB - Late Phase Emphasis Completed
CALGB-80303 CALGB A Randomized Phase III Trial of Gemcitabine Plus Bevacizumab (NSC #704865 IND# 7921) Versus Gemcitabine Plus Placebo in Patients with Advanced Pancreatic Cancer Adult CIRB - Late Phase Emphasis Completed
9824 ETCTN A Phase 1 Study of alisertib (MLN8237) in combination with mFOLFOX in gastrointestinal tumors Adult CIRB - Early Phase Emphasis Completed
AHOD0521 COG A Phase II Study of Bortezomib (Velcade; PS-341; IND # 58443) in Combination with Ifosfamide/Vinorelbine in Pediatric Patients and Young Adults with Refractory/Recurrent Hodgkin Disease: A Groupwide Phase II Study Pediatric CIRB Completed
S0227 SWOG Phase III Randomized Trial of Cisplatin/Paclitaxel Versus Cisplatin/Gemcitabine in Recurrent; Persistent; or Metastatic Carcinoma of the Cervix Adult CIRB - Late Phase Emphasis Completed
AAML06P1 COG A Pilot Study of Lestaurtinib (CEP-701) in Combination with Chemotherapy in Young Patients with Relapsed or Refractory FLT3-mutant Acute Myeloid Leukemia Pediatric CIRB Completed
AOST1322 COG A Phase II Study of Eribulin (IND# 122686; NSC# 707389) in Recurrent or Refractory Osteosarcoma: An Intergroup NCTN Phase II Study Pediatric CIRB Completed
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