CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| NSABP-C-08 | NSABP | A Phase III Clinical Trial Comparing Infusional 5-Fluorouracil (5-FU); Leucovorin; and Oxaliplatin (mFOLFOX6) Every Two Weeks with Bevacizumab to the Same Regimen without Bevacizumab for the Treatment of Patients with Resected Stages II and III Carcinoma of the Colon | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-C-09 | NSABP | A Phase III Clinical Trial Comparing Oxaliplatin; Capecitabine; and Hepatic Arterial Infusion of Floxuridine to Oxaliplatin and Capecitabine in Patients with Resected or Ablated Liver Metastases from Colorectal Cancer. | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-C-11 | NSABP | A Phase III Study Evaluating the Role of Perioperative Chemotherapy in Patients with Potentially Resectable Hepatic Colorectal Metastases | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-NCIC-CTG-MA.32.F | NSABP | Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NSABP-R-04 | NSABP | A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with or without Oxaliplatin with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-Fluorouracil with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma of the Rectum | Adult CIRB - Late Phase Emphasis | Completed |
| NWU20-01-03 | CLO-Northwestern University | Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD): RELIEF-NAFLD | Cancer Prevention and Control CIRB | Available to Open |
| NWU20-02-01 | CLO-Northwestern University | Surgical Window of Opportunity Study of Megestrol Acetate Compared with Megestrol Acetate and Metformin for Endometrial Intraepithelial Neoplasia | Cancer Prevention and Control CIRB | Available to Open |
| NWU20-02-02 | CLO-Northwestern University | A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant P53 By Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer | Cancer Prevention and Control CIRB | Available to Open |
| NWU20-04-01 | CLO-Northwestern University | Metformin for Chemoprevention of Lung Cancer in High-Risk Overweight or Obese Individuals | Cancer Prevention and Control CIRB | Available to Open |
| NWU2014-04-01 | CLO-Northwestern University | Statin Therapy to Reduce the Risk of Recurrent Pancreatitis | Cancer Prevention and Control CIRB | Completed |