CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| CALGB-30607 | CALGB | Randomized; Phase III; Double-Blind Placebo-Controlled Trial of Sunitinib (NSC #736511; IND #74019) as Maintenance Therapy in Non-Progressing Patients Following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced; Stage IIIB/IV Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| CALGB-90206 | CALGB | A Randomized Phase III Trial of Interferon Alfa-2B or Interferon Alfa-2B Plus Bevacizumab in Patients with Advanced Renal Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| ARST0531 | COG | Randomized Study of Vincristine; Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS): A Groupwide Phase III Study | Pediatric CIRB | Completed |
| E3201 | ECOG | Intergroup Randomized Phase III Study of Postoperative Irinotecan; 5-Fluorouracil and Leucovorin Vs Oxaliplatin; 5-Fluorouracil and Leucovorin Vs 5-Fluorouracil and Leucovorin For Patients with Stage II or III Rectal Cancer Receiving Either Preoperative Radiation and 5-Fluorouracil or Postoperative Radiation and 5-Fluorouracil | Adult CIRB - Late Phase Emphasis | Completed |
| 10349 | ETCTN | A Phase 1 Trial of the p97 Inhibitor CB-5339 in Patients With Advanced Solid Tumors and Lymphomas | Adult CIRB - Early Phase Emphasis | Completed |
| S9910 | SWOG | Leukemia Centralized Reference Laboratories and Tissue Repositories Ancillary | Adult CIRB - Late Phase Emphasis | Completed |
| AEPI05N1 | COG | Carcinogen Metabolism; DNA Repair; Parental Exposures and Retinoblastoma: A Groupwide Non-Therapeutic Study | Pediatric CIRB | Completed |
| AOST0331 | COG | A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histological Response to Pre-Operative Chemotherapy (IND# 12697): A Phase III Intergroup Study | Pediatric CIRB | Completed |
| ADVL0525 | COG | A Phase II Study of Pemetrexed in Children with Recurrent Malignancies | Pediatric CIRB | Completed |
| E1899 | ECOG | Phase III Randomized Trial for Evaluating Second Line Hormonal Therapy (Ketoconazole/Hydrocortisone) versus Docetaxel/Estramustine Combination Chemotherapy on Progression Free Survival in Asymptomatic Patients with a Rising PSA after Hormonal Therapy for Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |