CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| AREN0321 | COG | Treatment of High Risk Renal Tumors: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| ACCL1031 | COG | A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| NCICOVID | NCI | NCI COVID-19 in Cancer Patients Study (N-CCaPS): A Longitudinal Natural History Study | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-1010 | RTOG | A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| E3200 | ECOG | Phase III Trial of Bevacizumab (NSC 704865); Oxaliplatin (NSC 266046); Fluorouracil and Leucovorin versus Oxaliplatin; Fluorouracil and Leucovorin versus Bevacizumab Alone in Previously Treated Patients with Advanced Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ACNS0927 | COG | A Phase 1/2 Study of Suberoylanilide Hydroxamic Acid (SAHA; Vorinostat) and Local Irradiation; Followed By Maintenance SAHA in Children with Newly Diagnosed Diffuse Intrinsic Pontine Gliomas (DIPG) | Pediatric CIRB | Completed |
| AALL0433 | COG | Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies. A Groupwide Phase III Study | Pediatric CIRB | Completed |
| CALGB-10701 | CALGB | A Phase II Study of Dasatinib (Sprycel) (IND #73969; NSC #732517) as Primary Therapy Followed by Transplantation for Adults >/= 18 Years with Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia by CALGB; ECOG and SWOG | Adult CIRB - Late Phase Emphasis | Completed |
| A091603 | Alliance | A Randomized Phase II Trial of Adjuvant Nivolumab or Expectant Observation Following Neoadjuvant Ipilimumab Plus Nivolumab and Surgical Resection of High-Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma | Adult CIRB - Late Phase Emphasis | Completed |
| AOST1322 | COG | A Phase II Study of Eribulin (IND# 122686; NSC# 707389) in Recurrent or Refractory Osteosarcoma: An Intergroup NCTN Phase II Study | Pediatric CIRB | Completed |