CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| NHSR10.2021 | NCI | 21st Century Cures Act and PRA Implementation | Adult CIRB - Late Phase Emphasis | Completed |
| E2499 | ECOG | Randomized Phase III Trial of Rituximab (NSC #687451) and Autologous Stem Cell Transplantation for B Cell Diffuse Large Cell Lymphoma | Adult CIRB - Late Phase Emphasis | Completed |
| N0723 | NCCTG | MARVEL: Marker Validation of Erlotinib in Lung Cancer- A Phase III Biomarker Validation Study of Second-line Therapy in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Randomized to Pemetrexed Versus Erlotinib | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-P-0011 | RTOG | Phase III Randomized Study of Adjuvant Therapy For High Risk PT2-3N0 Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| AALL0331 | COG | Standard Risk B-precursor Acute Lymphoblastic Leukemia (ALL): A Phase III Group-Wide Study | Pediatric CIRB | Completed |
| ACCL0933 | COG | A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML): A Groupwide Phase III Study | Pediatric CIRB | Completed |
| E1Y03 | ECOG | Master Protocol for Pharmacogenetic and Genomic Studies. | Adult CIRB - Late Phase Emphasis | Completed |
| 10195 | ETCTN | A Phase 2 Study of Copanlisib (BAY 80-6946) in Combination with Fulvestrant in Women with Metastatic Breast Cancer Progressing After Aromatase Inhibitor Plus CDK 4/6 Inhibitor | Adult CIRB - Early Phase Emphasis | Completed |
| ACOSOG-Z9031 | ACSOG | A Phase III Randomized Study of Preoperative Radiation Plus Surgery Versus Surgery Alone for Patients with Retroperitoneal Sarcomas (RPS) | Adult CIRB - Late Phase Emphasis | Completed |
| ADVL06B1 | COG | A Pharmacokinetic-Pharmacodynamic-Pharmacogenetic Study of Actinomycin-D and Vincristine in Children with Cancer: A Group-Wide Non-Therapeutic Study | Pediatric CIRB | Completed |