CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
Study Number | Lead Group | Study Title | CIRB | Study Status |
---|---|---|---|---|
ACNS1721 | COG | A Phase 2 Study of Veliparib (ABT-888, IND # 139199) and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients with Newly Diagnosed High-Grade Glioma (HGG) without H3 K27M or BRAFV600E Mutations | Pediatric CIRB | Available to Open |
ABTR04B1 | COG | Establishing Continuous Cell Lines and Xenografts from Pediatric Cancers for Biological and Pre-Clinical Therapeutic Studies | Pediatric CIRB | Available to Open |
ACNS0621 | COG | Cilengitide (EMD 121974) (IND# 59073) in Recurrent or Progressive and Refractory Childhood High-Grade Glioma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
AAML0121 | COG | "A Phase II Study of Amifostine In Children with Myelodysplastic Syndrome: A Group-wide Study" | Pediatric CIRB | Completed |
AHOD0831 | COG | A Non-Randomized Phase III Study of Response Adapted Therapy for the Treatment of Children with Newly Diagnosed High Risk Hodgkin Lymphoma: A Groupwide Phase III Study | Pediatric CIRB | Completed |
ANBL0931 | COG | A Comprehensive Safety Trial of Chimeric Antibody 14.18 (ch14.18) with GM-CSF, IL-2 and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy | Pediatric CIRB | Completed |
ACCL1131 | COG | A Phase III Open-Label Trial of Caspofungin vs. Azole Prophylaxis for Patients at High-Risk for Invasive Fungal Infections (IFI) Following Allogeneic Hematopoietic Cell Transplantation (HCT) | Pediatric CIRB | Completed |
ADVL0821 | COG | A Phase II Study of IMC-A12 (Anti-IGF-I Receptor Monoclonal Antibody; IND# 100947; NSC# 742460) in Children with Relapsed/Refractory Solid Tumors: A COG Groupwide Phase II Study | Pediatric CIRB | Completed |
ALTE16C1 | COG | Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma | Pediatric CIRB | Available to Open |
AREN1721 | COG | A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Axitinib or Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups | Pediatric CIRB | Available to Open |