CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A091802 | Alliance | Phase II Randomized Trial of Avelumab Plus Cetuximab versus Avelumab Alone in Advanced Cutaneous Squamous Cell Carcinoma of the Skin (cSCC) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A022104 | Alliance | The Janus Rectal Cancer Trial: A Randomized Phase II Trial Testing the Efficacy of Triplet versus Doublet Chemotherapy to Achieve Clinical Response in Patients with Locally Advanced Rectal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A051701 | Alliance | Randomized Phase II/III Study of Venetoclax (ABT 199) Plus Chemoimmunotherapy for MYC/BCL2 Double-Hit and Double-Expressing Lymphomas | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071601 | Alliance | Phase II Trial of BRAF/MEK Inhibitors in Papillary Craniopharyngiomas | Adult CIRB - Late Phase Emphasis | Available to Open |
| A022106 | Alliance | Phase II/III Second-Line NABPLAGEM vs. Nab-Paclitaxel/Gemcitabine in BRCA1/2 or PALB2 Mutant Metastatic Pancreatic Ductal Adenocarcinoma (PLATINUM) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A031801 | Alliance | A Phase II Randomized Trial of Radium-223 Dichloride and Cabozantinib in Patients with Advanced Renal Cell Carcinoma with Bone Metastasis (RADICAL) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A191901 | Alliance | Optimizing Endocrine Therapy Through Motivational Interviewing and Text Interventions | Cancer Prevention and Control CIRB | Available to Open |
| A082002 | Alliance | A Randomized Phase II/III Trial of Modern Immunotherapy Based Systemic Therapy with or without SBRT for PD-L1-Negative, Advanced Non-small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A051301 | Alliance | A Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma of the Activated B-Cell Subtype | Adult CIRB - Late Phase Emphasis | Available to Open |
| A221208 | Alliance | Randomized Phase II Study: Corticosteroids and Bevacizumab vs. Corticosteroids and Placebo (BeSt) for Radionecrosis after Radiosurgery for Brain Metastases | Cancer Prevention and Control CIRB | Available to Open |