CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ADVL1515 | COG | A Phase 1 Study of LY2606368, (prexasertib mesylate monohydrate) (IND# 132233), a CHK1/2 Inhibitor, in Pediatric Patients with Recurrent or Refractory Solid Tumors, including CNS Tumors | Pediatric CIRB | Completed |
| ASCT0631D | COG | A Comparison of Acute and Long-term Toxicities in Bone Marrow Donors with and without G-CSF Treatment Prior to Harvest: A Companion Study to ASCT0631 | Pediatric CIRB | Completed |
| ADVL06B1 | COG | A Pharmacokinetic-Pharmacodynamic-Pharmacogenetic Study of Actinomycin-D and Vincristine in Children with Cancer: A Group-Wide Non-Therapeutic Study | Pediatric CIRB | Completed |
| PBTC-053 | PBTC | A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma | Pediatric CIRB | Available to Open |
| AALL07P4 | COG | A Pilot Study of Intravenous EZN-2285 (SC-PEG E. coli L-asparaginase; IND# 100594) or Intravenous Oncaspar in the Treatment of Patients with High-Risk Acute Lymphoblastic Leukemia (ALL): A Limited Institution Pilot Study | Pediatric CIRB | Completed |
| ANBL0931 | COG | A Comprehensive Safety Trial of Chimeric Antibody 14.18 (ch14.18) with GM-CSF, IL-2 and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy | Pediatric CIRB | Completed |
| ARST0921 | COG | A Randomized Phase II Trial of Bevacizumab (IND# 7921; Avastin) and Temsirolimus (IND# 61010; Torisel) in Combination with Intravenous Vinorelbine and Cyclophosphamide in Patients with Recurrent/Refractory Rhabdomyosarcoma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| AAML18P1 | COG | Stopping Tyrosine Kinase Inhibitors (TKI) to Assess Treatment-Free Remission (TFR) in Pediatric Chronic Myeloid Leukemia - Chronic Phase (CML-CP) | Pediatric CIRB | Available to Open |
| AHOD03P1 | COG | Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study | Pediatric CIRB | Available to Open |
| AAML1531 | COG | Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome: A COG Groupwide Phase III Study | Pediatric CIRB | Available to Open |