CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ARET0231 | COG | A Single Arm Trial of Systemic and Subtenon Chemotherapy for Groups C and D Intraocular Retinoblastoma | Pediatric CIRB | Completed |
| ACCL0431 | COG | A Randomized Phase III Study of Sodium Thiosulfate (IND#72877; NSC#45624) for the Prevention of Cisplatin-Induced Ototoxicity in Children: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| AGCT1532 | COG | Phase 3 Accelerated BEP Trial: A randomized phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumors | Pediatric CIRB | Available to Open |
| ANHL12P1 | COG | A Randomized Phase II Trial of Brentuximab Vedotin (SGN35; NSC# 749710) or Crizotinib (NSC#749005; commercially labeled) in Combination with Chemotherapy for Newly Diagnosed Patients with Anaplastic Large Cell Lymphoma (ALCL) IND # 117117 | Pediatric CIRB | Available to Open |
| SCUSF-0901 | COG | SCUSF 0901 [ACCL0922] A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor | Pediatric CIRB | Available to Open |
| ACCL20N1CD | COG | Financial Distress during Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States | Pediatric CIRB | Available to Open |
| AAML1031 | COG | A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239; NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD | Pediatric CIRB | Available to Open |
| ACNS1221 | COG | A Phase II Study For The Treatment Of Non-Metastatic Nodular Desmoplastic Medulloblastoma In Children Less Than 4 Years Of Age: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| ALTE21C1 | COG | Assessment of Clonal Hematopoiesis and its Relationship to Cardiovascular Disease in Hodgkin Lymphoma Survivors | Pediatric CIRB | Available to Open |
| ANBL1821 | COG | A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or without Eflornithine (DFMO) (IND# TBD) in Children with Relapsed, Refractory or Progressive Neuroblastoma | Pediatric CIRB | Available to Open |