CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 920
Study Number Lead Group Study Title CIRB Study Status
10146 ETCTN Randomized phase 2 clinical trial of nab-paclitaxel + MEDI4736 (durvalumab) + tremelimumab + neoantigen vaccine vs. nab-paclitaxel + MEDI4736 (durvalumab) + tremelimumab in patients with metastatic triple negative breast cancer Adult CIRB - Early Phase Emphasis Available to Open
S1614 SWOG A Phase III Randomized Trial of Prophylactic Antiviral Therapy in Patients with Current or Past Hepatitis B Virus (HBV) Infection Receiving Anti-Cancer Therapy for Solid Tumors Cancer Prevention and Control CIRB Available to Open
ACNS0821 COG Temozolomide with Irinotecan versus Temozolomide; Irinotecan plus Bevacizumab (NSC# 704865; BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood; A COG Randomized Phase II Screening Trial: A Groupwide Phase II Study Pediatric CIRB Available to Open
A011502 Alliance A Randomized Phase III Double Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial Adult CIRB - Late Phase Emphasis Available to Open
RTOG-1115 RTOG Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 For Men with High Risk Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
AAML1531 COG Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome: A COG Groupwide Phase III Study Pediatric CIRB Available to Open
10302 ETCTN Phase II Trial of Radium-223 Dichloride in Combination with Paclitaxel in Patients with Bone Metastatic Breast Cancer Adult CIRB - Early Phase Emphasis Available to Open
EA2187 ECOG-ACRIN A Phase 2 Study of Pevonedistat in Combination with Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma Adult CIRB - Late Phase Emphasis Available to Open
S1203 SWOG A Randomized Phase III Study of Standard Cytarabine plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) versus IA with Vorinostat (NSC-701852) (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML) Adult CIRB - Late Phase Emphasis Available to Open
E1A06 ECOG An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan; Prednisone and Thalidomide (MPT) Versus Melphalan; Prednisone and Lenalidomide (Revlimid TM) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy Adult CIRB - Late Phase Emphasis Available to Open
Displaying 1 - 10 of 920