CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 964
Study Number Lead Group Study Title CIRB Study Status
EA5161 ECOG-ACRIN Randomized Phase II Clinical Trial of Cisplatin/Carboplatin and Etoposide (CE) alone or in Combination with Nivolumab as Frontline Therapy for Extensive Stage Small Cell Lung Cancer (ED-SCLC) Adult CIRB - Late Phase Emphasis Available to Open
A011502 Alliance A Randomized Phase III Double Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial Adult CIRB - Late Phase Emphasis Available to Open
NRG-GY001 NRG A Phase II Trial of Cabozantinib (XL-184) (NSC #761968) in Women with Recurrent; Clear Cell Carcinoma of the Ovary; Fallopian Tube; or Peritoneum Adult CIRB - Late Phase Emphasis Completed
TRC-10446 NCI Tocilizumab in Hospitalized Cancer Patients with Coronavirus 2019 (SARS-CoV-2) and Severe Complications of Coronavirus Disease 19 (COVID-19) Adult CIRB - Late Phase Emphasis Available to Open
A031902 Alliance CASPAR - A Phase III Trial of Enzalutamide and Rucaparib as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
S1505 SWOG A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/NAB-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma Adult CIRB - Late Phase Emphasis Available to Open
S1616 SWOG A Phase II Randomized Study of Nivolumab (NSC-748726) with Ipilimumab (NSC-732442) or Ipilimumab Alone in Advanced Melanoma Patients Refractory to an Anti-PD1 or Anti-PD-L1 Agent Adult CIRB - Late Phase Emphasis Available to Open
NSABP-B-42 NSABP A Clinical Trial to Determine the Efficacy of Five Years of Letrozole Compared to Placebo in Patients Completing Five Years of Hormonal Therapy Consisting of an Aromatase Inhibitor (AI) or Tamoxifen Followed by an AI in Prolonging Disease-Free Survival in Postmenopausal Women with Hormone Receptor Positive Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
A091603 Alliance A Randomized Phase II Trial of Adjuvant Nivolumab or Expectant Observation Following Neoadjuvant Ipilimumab Plus Nivolumab and Surgical Resection of High-Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma Adult CIRB - Late Phase Emphasis Completed
S0819 SWOG A Randomized; Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) Adult CIRB - Late Phase Emphasis Available to Open
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