CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 920
Study Number Lead Group Study Title CIRB Study Status
EA5182 ECOG-ACRIN Randomized Phase III Study of Combination AZD9291 (osimertinib) and Bevacizumab versus AZD9291 (osimertinib) Alone as First-Line Treatment for Patients with Metastatic EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC) Adult CIRB - Late Phase Emphasis Available to Open
CALGB-10701 CALGB A Phase II Study of Dasatinib (Sprycel) (IND #73969; NSC #732517) as Primary Therapy Followed by Transplantation for Adults >/= 18 Years with Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia by CALGB; ECOG and SWOG Adult CIRB - Late Phase Emphasis Available to Open
EA1181 ECOG-ACRIN (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response Adult CIRB - Late Phase Emphasis Available to Open
CALGB-90104 CALGB A Randomized Phase III Study Comparing Sequential Chemotherapy (AG-TP) to Cisplatin and Gemcitabine as Adjuvant Treatment After Cystectomy for Transitional Cell Carcinoma of the Bladder Adult CIRB - Late Phase Emphasis Completed
NRG-BN009 NRG Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse after Upfront SRS with Brain Metastasis Velocity ≥4 Brain Metastases/Year Adult CIRB - Late Phase Emphasis Available to Open
LungMAP SWOG A Master Protocol to Evaluate Biomarker-Driven Therapies and Immunotherapies in Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Screening Study) Adult CIRB - Late Phase Emphasis Available to Open
EA8143 ECOG-ACRIN A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) Adult CIRB - Late Phase Emphasis Available to Open
NSABP-B-34 NSABP A Clinical Trial Comparing Adjuvant Clodronate Therapy vs. Placebo in Early-Stage Breast Cancer Patients Receiving Systemic Chemotherapy and/or Hormonal Therapy or No Therapy Adult CIRB - Late Phase Emphasis Completed
E5202 ECOG A Randomized Phase III Study Comparing 5-FU; Leucovorin and Oxaliplatin Versus 5-FU; Leucovorin; Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers Adult CIRB - Late Phase Emphasis Available to Open
S1602 SWOG A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Nave High-Grade Non-Muscle Invasive Bladder Cancer Adult CIRB - Late Phase Emphasis Available to Open
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