CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
Study Number | Lead Group | Study Title | CIRB | Study Status |
---|---|---|---|---|
A031201 | Alliance | Phase III Trial of Enzalutamide (NSC # 766085) Versus Enzalutamide; Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
NSABP-NCIC-CTG-MA.32.F | NSABP | Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
GOG-0275 | GOG | A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia | Adult CIRB - Late Phase Emphasis | Completed |
CALGB-90104 | CALGB | A Randomized Phase III Study Comparing Sequential Chemotherapy (AG-TP) to Cisplatin and Gemcitabine as Adjuvant Treatment After Cystectomy for Transitional Cell Carcinoma of the Bladder | Adult CIRB - Late Phase Emphasis | Completed |
A082101 | Alliance | Multimodality Therapy with Immunotherapy in Stage I-IIIA Sarcomatoid Mesothelioma | Adult CIRB - Late Phase Emphasis | Available to Open |
E5202 | ECOG | A Randomized Phase III Study Comparing 5-FU; Leucovorin and Oxaliplatin Versus 5-FU; Leucovorin; Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers | Adult CIRB - Late Phase Emphasis | Available to Open |
E1A00 | ECOG | A Randomized Phase III Trial of Thalidomide (NSC #66847) Plus Dexamethasone Versus Dexamethasone in Newly Diagnosed Multiple Myeloma | Adult CIRB - Late Phase Emphasis | Completed |
EA5163 | ECOG-ACRIN | INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature-driven Analysis | Adult CIRB - Late Phase Emphasis | Available to Open |
NRG-LU001 | NRG | Randomized Phase II Trial of Concurrent Chemoradiotherapy +/- Metformin HCL in Locally Advanced NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |
RTOG-0724 | RTOG | Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy | Adult CIRB - Late Phase Emphasis | Available to Open |