CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| MAY2016-08-01 | CLO-Mayo Clinic | A Pilot Study of MUC1 Vaccine in Current and Former Smokers at High Risk for Lung Cancer | Cancer Prevention and Control CIRB | Available to Open |
| ALTE03N1 | COG | Key Adverse Events after Childhood Cancer | Pediatric CIRB | Available to Open |
| NRG-HN006 | NRG | Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| PBTC-055 | PBTC | Phase I/II trial of Dabrafenib, Trametinib, and Hydroxychloroquine (HCQ) for BRAF V600E-mutant or Trametinib and HCQ for BRAF fusion/duplication positive or NF1-associated recurrent or progressive gliomas in children and young adults | Pediatric CIRB | Available to Open |
| S1602 | SWOG | A Phase III Randomized Trial to Evaluate the Influence of BCG Strain Differences and T Cell Priming with Intradermal BCG Before Intravesical Therapy for BCG-Nave High-Grade Non-Muscle Invasive Bladder Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| ANHL12P1 | COG | A Randomized Phase II Trial of Brentuximab Vedotin (SGN35; NSC# 749710) or Crizotinib (NSC#749005; commercially labeled) in Combination with Chemotherapy for Newly Diagnosed Patients with Anaplastic Large Cell Lymphoma (ALCL) IND # 117117 | Pediatric CIRB | Available to Open |
| AALL1631 | COG | International Phase 3 trial in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) testing imatinib in combination with two different cytotoxic chemotherapy backbones | Pediatric CIRB | Available to Open |
| A091304 | Alliance | A Phase I /Randomized Phase II Study of MLN0128 (TAK-228) vs. Pazopanib In Patients With Locally Advanced/Unresectable And/Or Metastatic Sarcoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-GY007 | NRG | A Phase I/II Study of Ruxolitinib with Front-Line Neoadjuvant and Post-Surgical Therapy in Patients with Advanced Epithelial Ovarian; Fallopian Tube; or Primary Peritoneal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1801 | SWOG | A Phase II Randomized Study of Adjuvant versus Neoadjuvant MK-3475 (Pembrolizumab) for Clinically Detectable Sage III-IV High Risk Melanoma | Adult CIRB - Late Phase Emphasis | Available to Open |